This calculator is designed as an additional information tool for healthcare professionals to conveniently calculate the dose and regimen of modern high-dose intravenous iron preparations in iron-deficient patients who are indicated for appropriate therapy. The calculator was developed on the basis of the instructions for the medical use of the drug ferric carboxymaltose.
- determination of individual need for iron;
- calculation and administration of dose(s) of iron;
- assessment of the saturation of the patient's body with iron after administration.
Determination of individual iron needs
The individual iron requirement for replenishment with ferric carboxymaltose is determined based on the patient's body weight and hemoglobin (Hb) level.
Recommended iron requirement and mode of administration:
With a single administration of the drug Ferric Carboxymaltose by infusion the dose should not exceed:
15 mg/KG for bolus injection body weight
With a single administration of the drug ferric carboxymaltose by injection the dose should not exceed:
15 mg/KG for bolus injection body weight
The maximum recommended total dose of ferric carboxymaltose per week is:
1000mg of iron (15 ml of ferric carboxymaltose).
Single dose of ferric carboxymaltose and method of administration:
Immediately before the infusion, the drug must be diluted with a sterile 0.9% sodium chloride solution for injection.
1To maintain the stability of the drug, dilution to concentrations of less than 2 mg of iron / ml is not allowed (the volume of the solution of the drug ferric carboxymaltose is not taken into account).
Each patient should be observed for the development of signs or symptoms of hypersensitivity reactions for at least 30 minutes after each administration of ferric carboxymaltose.
Children under 14 years of age are a contraindication to the use of the ferric carboxyMaltose
After replenishing iron levels, regular assessments should be made to make sure that iron levels have returned to normal and are maintained at the proper level.
Hb levels should be assessed no earlier than 4 weeks after the last use of ferric carboxymaltose to allow sufficient time for erythropoiesis and iron absorption.
If the patient needs further replenishment of reserves, then the need for iron must be recalculated.
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Iron deficiency must be confirmed by laboratory tests.